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Literature summary for 3.4.21.39 extracted from

  • Wei, C.C.; Hase, N.; Inoue, Y.; Bradley, E.W.; Yahiro, E.; Li, M.; Naqvi, N.; Powell, P.C.; Shi, K.; Takahashi, Y.; Saku, K.; Urata, H.; Dellitalia, L.J.; Husain, A.
    Mast cell chymase limits the cardiac efficacy of Ang I-converting enzyme inhibitor therapy in rodents (2010), J. Clin. Invest., 120, 1229-1239.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.39

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasmic vesicle
-
 Mus musculus 31410
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart interstitial fluid from left ventricle Mus musculus
-
mast cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
angiotensin I + H2O
-
 Mus musculus angiotensin II + ?
-
 ?

Synonyms

Synonyms Comment Organism
mast cell chymase
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus chronic angiotensin I-converting enzyme inhibition causes a marked bradykinin/B2 receptor-mediated increase in left ventricle interstitial fluid chymase activity up

General Information

General Information Comment Organism
malfunction chymase inhibition improves LV function and decreases adverse cardiac remodeling after myocardial infarction Mus musculus