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Literature summary for 3.4.21.39 extracted from

  • Tashiro, K.; Takai, S.; Jin, D.; Yamamoto, H.; Komeda, K.; Hayashi, M.; Tanaka, K.; Tanigawa, N.; Miyazaki, M.
    Chymase inhibitor prevents the nonalcoholic steatohepatitis in hamsters fed a methionine- and choline-deficient diet (2010), Hepatol. Res., 40, 514-523.
    View publication on PubMed
Search for more literature for 3.4.21.39

Inhibitors

Inhibitors Comment Organism Structure
2-[4-(5-fluoro-3-methylbenzo[b]thiophen-2-yl)sulfonamido-3-methanesulfonylphenyl]thiazole-4-carboxylic acid TY-51469, specific chymase inhibitor Mesocricetus auratus

Organism

Organism UniProt Comment Textmining
Mesocricetus auratus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Mesocricetus auratus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
angiotensin I + H2O
-
 Mesocricetus auratus angiotensin II + ?
-
 ?
pro-matrix metalloprotease 9 + H2O
-
 Mesocricetus auratus matrix metalloprotease 9 + ?
-
 ?

General Information

General Information Comment Organism
physiological function chymase may play a crucial role in the development of nonalcoholic steatohepatitis in hamsters Mesocricetus auratus