Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.39 extracted from

  • Togawa, H.; Nakanishi, K.; Shima, Y.; Obana, M.; Sako, M.; Nozu, K.; Tanaka, R.; Iijima, K.; Yoshikawa, N.
    Increased chymase-positive mast cells in children with crescentic glomerulonephritis (2009), Pediatr. Nephrol., 24, 1071-1075.
    View publication on PubMed
Search for more literature for 3.4.21.39

Activating Compound

Activating Compound Comment Organism Structure
additional information chymase has no enzymatic activity under normal physiological conditions, but it is activated immediately after release into the extracellular matrix Homo sapiens

Application

Application Comment Organism
medicine mast cell-derived chymase plays an important role in juvenile crescentic glomerulonephritis Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
angiotensin I + H2O Homo sapiens
-
 angiotensin II + His-Leu
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Homo sapiens
-
mast cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
angiotensin I + H2O
-
 Homo sapiens angiotensin II + His-Leu
-
 ?

Synonyms

Synonyms Comment Organism
mast cell-derived chymase
-
 Homo sapiens
MC-derived chymase
-
 Homo sapiens