Inhibitors | Comment | Organism | Structure |
---|---|---|---|
rHA-infestin-4 | serine protease inhibitor isolated from Triatoma infestans | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
factor XI + H2O | Mus musculus | - |
factor XIa + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Mus musculus | P00748 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
factor XI + H2O | - |
Mus musculus | factor XIa + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
blood coagulation factor XII | - |
Mus musculus |
blood coagulation factor XII | serine protease | Mus musculus |
FXII | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | hereditary factor XII deficiency does not induce any bleeding phenotype. FXII deficiency prevents pathological thrombus formation, but does not affect regular hemostasis | Mus musculus |
physiological function | activated by contact with negatively charged surfaces, involved in clot formation | Mus musculus |
physiological function | blood coagulation factor XII initiates the intrinsic pathway of coagulation which, together with the extrinsic pathway, culminates in the formation of fibrin | Mus musculus |