Application | Comment | Organism |
---|---|---|
medicine | after transient middle cerebral artery occlusion, the volume of infarcted brain in enzyme-deficient or enzyme-inhibitor treated mice is substantially less than in control, without an increase in infarct-associated hemorrhage | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | enzyme deletion mutant, protects mice from ischemic brain injury | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
PCK | factor XIIa inhibitor, protects mice from ischemic brain injury | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | enzyme contributes to pathologic clotting through the intrinsic pathway | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | enzyme contributes to pathologic clotting through the intrinsic pathway | Mus musculus | ? | - |
? |