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Literature summary for 3.4.21.37 extracted from

  • Luna-Gomes, T.; Filardy, A.A.; Rocha, J.D.; Decote-Ricardo, D.; LaRocque-de-Freitas, I.F.; Morrot, A.; Bozza, P.T.; Castro-Faria-Neto, H.C.; DosReis, G.A.; Nunes, M.P.; Freire-de-Lima, C.G.
    Neutrophils increase or reduce parasite burden in Trypanosoma cruzi-infected macrophages, depending on host strain: role of neutrophil elastase (2014), PLoS ONE, 9, e90582.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
methoxysuccinyl-Ala-Ala-Pro-Val-chloromethylketone specific inhibitor Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Elastin + H2O Mus musculus
-
?
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
neutrophil
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Elastin + H2O
-
Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
neutrophil elastase
-
Mus musculus

General Information

General Information Comment Organism
physiological function addition of neutrophil elastase to Trypanosoma cruzi-infected macrophages reduced the replication of the parasites Mus musculus