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Literature summary for 3.4.21.37 extracted from
- Synthesis and biological evaluation of nigranoic acid esters as novel human neutrophil elastase inhibitors (2015), Nat. Prod. Res., 29, 1650-1656.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| nigranoic acid | significant inhibitory activity | Homo sapiens |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Elastin + H2O | Homo sapiens | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Elastin + H2O | - |
Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| HNE | - |
Homo sapiens |
| neutrophil elastase | - |
Homo sapiens |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.00377 | - |
pH and temperature not specified in the publication | Homo sapiens | nigranoic acid | |
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