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Literature summary for 3.4.21.37 extracted from

  • Sienczyk, M.; Winiarski, L.; Kasperkiewicz, P.; Psurski, M.; Wietrzyk, J.; Oleksyszyn, J.
    Simple phosphonic inhibitors of human neutrophil elastase (2011), Bioorg. Med. Chem. Lett., 21, 1310-1314.
    View publication on PubMed
Search for more literature for 3.4.21.37

Inhibitors

Inhibitors Comment Organism Structure
bis(2,3,5-trimethylphenyl) (1-[[(benzyloxy)carbonyl]amino]-3-methylbutyl)phosphonate
-
 Homo sapiens
bis(2,3-dimethylphenyl) (1-[[(benzyloxy)carbonyl]amino]-3-methylbutyl)phosphonate
-
 Homo sapiens
bis(2-methylphenyl) (1-[[(benzyloxy)carbonyl]amino]-3-methylbutyl)phosphonate
-
 Homo sapiens
bis(3,4,5-trimethylphenyl) (1-[[(benzyloxy)carbonyl]amino]-3-methylbutyl)phosphonate
-
 Homo sapiens
bis(3,4-dimethylphenyl) (1-[[(benzyloxy)carbonyl]amino]-3-methylbutyl)phosphonate
-
 Homo sapiens
bis(3-chlorophenyl) (1-[[(benzyloxy)carbonyl]amino]-3-methylbutyl)phosphonate
-
 Homo sapiens
bis(3-chlorophenyl) (1-[[(benzyloxy)carbonyl]amino]propyl)phosphonate
-
 Homo sapiens
bis(4-chlorophenyl) (1-[[(benzyloxy)carbonyl]amino]-3-methylbutyl)phosphonate
-
 Homo sapiens
bis(4-chlorophenyl) (1-[[(benzyloxy)carbonyl]amino]pentyl)phosphonate
-
 Homo sapiens
bis(4-chlorophenyl) (1-[[(benzyloxy)carbonyl]amino]propyl)phosphonate
-
 Homo sapiens
bis(4-ethylphenyl) (1-[[(benzyloxy)carbonyl]amino]-2-methylpropyl)phosphonate
-
 Homo sapiens
bis(4-ethylphenyl) (1-[[(benzyloxy)carbonyl]amino]-3-methylbutyl)phosphonate
-
 Homo sapiens
bis(4-ethylphenyl) (1-[[(benzyloxy)carbonyl]amino]butyl)phosphonate
-
 Homo sapiens
bis(4-ethylphenyl) (1-[[(benzyloxy)carbonyl]amino]ethyl)phosphonate
-
 Homo sapiens
bis(4-ethylphenyl) (1-[[(benzyloxy)carbonyl]amino]propyl)phosphonate
-
 Homo sapiens
bis(4-methoxyphenyl) (1-[[(benzyloxy)carbonyl]amino]-2-methylpropyl)phosphonate
-
 Homo sapiens
bis(4-methoxyphenyl) (1-[[(benzyloxy)carbonyl]amino]pentyl)phosphonate
-
 Homo sapiens
bis(4-methoxyphenyl) (1-[[(benzyloxy)carbonyl]amino]propyl)phosphonate
-
 Homo sapiens
bis(4-methylphenyl) (1-[[(benzyloxy)carbonyl]amino]-3-methylbutyl)phosphonate
-
 Homo sapiens
bis(4-tert-butylphenyl) (1-[[(benzyloxy)carbonyl]amino]-2-methylpropyl)phosphonate
-
 Homo sapiens
bis(4-tert-butylphenyl) (1-[[(benzyloxy)carbonyl]amino]-3-methylbutyl)phosphonate
-
 Homo sapiens
bis(4-tert-butylphenyl) (1-[[(benzyloxy)carbonyl]amino]ethyl)phosphonate
-
 Homo sapiens
bis(4-tert-butylphenyl) (1-[[(benzyloxy)carbonyl]amino]pentyl)phosphonate
-
 Homo sapiens
bis[3-(methylsulfanyl)phenyl] (1-[[(benzyloxy)carbonyl]amino]-3-methylbutyl)phosphonate
-
 Homo sapiens
bis[4-(methylsulfanyl)phenyl] (1-[[(benzyloxy)carbonyl]amino]-2-methylpropyl)phosphonate
-
 Homo sapiens
bis[4-(methylsulfanyl)phenyl] (1-[[(benzyloxy)carbonyl]amino]-3-methylbutyl)phosphonate
-
 Homo sapiens
bis[4-(methylsulfanyl)phenyl] (1-[[(benzyloxy)carbonyl]amino]butyl)phosphonate
-
 Homo sapiens
bis[4-(methylsulfanyl)phenyl] (1-[[(benzyloxy)carbonyl]amino]ethyl)phosphonate
-
 Homo sapiens
bis[4-(methylsulfanyl)phenyl] (1-[[(benzyloxy)carbonyl]amino]propyl)phosphonate
-
 Homo sapiens
bis[4-(propan-2-yl)phenyl] (1-[[(benzyloxy)carbonyl]amino]-3-methylbutyl)phosphonate
-
 Homo sapiens
bis[4-(propan-2-yl)phenyl] (1-[[(benzyloxy)carbonyl]amino]ethyl)phosphonate
-
 Homo sapiens
bis[4-(propan-2-yl)phenyl] (1-[[(benzyloxy)carbonyl]amino]pentyl)phosphonate
-
 Homo sapiens
bis[4-(propan-2-yl)phenyl] (1-[[(benzyloxy)carbonyl]amino]propyl)phosphonate
-
 Homo sapiens
dimethyl 3,3'-[[(1-[[(benzyloxy)carbonyl]amino]-3-methylbutyl)phosphoryl]bis(oxy)]dibenzoate
-
 Homo sapiens
dimethyl 4,4'-[[(1-[[(benzyloxy)carbonyl]amino]-2-methylpropyl)phosphoryl]bis(oxy)]dibenzenesulfinate
-
 Homo sapiens
dimethyl 4,4'-[[(1-[[(benzyloxy)carbonyl]amino]-2-methylpropyl)phosphoryl]bis(oxy)]dibenzoate
-
 Homo sapiens
dimethyl 4,4'-[[(1-[[(benzyloxy)carbonyl]amino]-3-methylbutyl)phosphoryl]bis(oxy)]dibenzoate
-
 Homo sapiens
dimethyl 4,4'-[[(1-[[(benzyloxy)carbonyl]amino]butyl)phosphoryl]bis(oxy)]dibenzoate
-
 Homo sapiens
dimethyl 4,4'-[[(1-[[(benzyloxy)carbonyl]amino]ethyl)phosphoryl]bis(oxy)]dibenzoate
-
 Homo sapiens
dimethyl 4,4'-[[(1-[[(benzyloxy)carbonyl]amino]pentyl)phosphoryl]bis(oxy)]dibenzoate
-
 Homo sapiens
dimethyl 4,4'-[[(1-[[(benzyloxy)carbonyl]amino]propyl)phosphoryl]bis(oxy)]dibenzoate
-
 Homo sapiens
diphenyl (1-[[(benzyloxy)carbonyl]amino]-3-methylbutyl)phosphonate
-
 Homo sapiens
diphenyl (1-[[(benzyloxy)carbonyl]amino]butyl)phosphonate
-
 Homo sapiens
diphenyl (1-[[(benzyloxy)carbonyl]amino]ethyl)phosphonate
-
 Homo sapiens
diphenyl (1-[[(benzyloxy)carbonyl]amino]pentyl)phosphonate
-
 Homo sapiens
diphenyl (1-[[(benzyloxy)carbonyl]amino]propyl)phosphonate
-
 Homo sapiens
sivelestat
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-methoxysuccinyl-Ala-Ala-Pro-Val-4-nitroanilide + H2O
-
 Homo sapiens N-methoxysuccinyl-Ala-Ala-Pro-Val + 4-nitroaniline
-
 ?

Synonyms

Synonyms Comment Organism
HNE
-
 Homo sapiens
neutrophil elastase
-
 Homo sapiens