Literature summary for 3.4.21.37 extracted from

Wei, L.; Lai, Z.; Gan, X.; Alliston, K.R.; Zhong, J.; Epp, J.B.; Tu, J.; Perera, A.B.; Van Stipdonk, M.; Groutas, W.C.
Mechanism-based inactivation of human leukocyte elastase via an enzyme-induced sulfonamide fragmentation process (2004), Arch. Biochem. Biophys., 429, 60-70.

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Inhibitors

Inhibitors	Comment	Organism	Structure
(R)-3-phenyl-2-(1,1,3-trioxo-1,3-dihydro-1lambda6-1,2-benzisothiazol-2-yl-methanesulfonylamino)-propionic acid methyl ester	-	Homo sapiens
(S)-3-phenyl-2-(1,1,3-trioxo-1,3-dihydro-1lambda6-1,2-benzisothiazol-2-yl-methanesulfonylamino)-propionic acid methyl ester	-	Homo sapiens
additional information	shows no activity as inhibitor	Homo sapiens
N-(2,2-diphenyl-ethyl)-1-(1,1,3-trioxo-1,3-dihydro-1lambda6-1,2-benzisothiazol-2-yl)-methanesulfonamide	-	Homo sapiens
N-benzyl-1-(1,1,3-trioxo-1,3-dihydro-1lambda6-1,2-benzisothiazol-2-yl)-methanesulfonamide	-	Homo sapiens
N-phenethyl-1-(1,1,3-trioxo-1,3-dihydro-1lambda6-1,2-benzisothiazol-2-yl)-methanesulfonamide	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

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Release 2023.1 (January 2023)