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Literature summary for 3.4.21.36 extracted from

  • Matthew, S.; Paul, V.J.; Luesch, H.
    Tiglicamides A-C, cyclodepsipeptides from the marine cyanobacterium Lyngbya confervoides (2009), Phytochemistry, 70, 2058-2063.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.36

Inhibitors

Inhibitors Comment Organism Structure
largamide A
-
 Sus scrofa
largamide A methyl ester low-micromolar inhibitory activity Sus scrofa
largamide B
-
 Sus scrofa
largamide B methyl ester low-micromolar inhibitory activity Sus scrofa
largamide C
-
 Sus scrofa
largamide C methyl ester low-micromolar inhibitory activity Sus scrofa
tiglicamide A moderate inhibition of porcine pancreatic elastase in vitro Sus scrofa
tiglicamide B moderate inhibition of porcine pancreatic elastase in vitro Sus scrofa
tiglicamide C moderate inhibition of porcine pancreatic elastase in vitro Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Elastin + H2O Sus scrofa
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Elastin + H2O
-
 Sus scrofa ?
-
 ?
succinyl-L-Ala-L-Ala-L-Pro-L-Ile-4-nitroanilide + H2O
-
 Sus scrofa ?
-
 ?

Synonyms

Synonyms Comment Organism
elastase
-
 Sus scrofa

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00053
-
-
 Sus scrofa largamide B
0.00115
-
-
 Sus scrofa largamide C
0.00141
-
-
 Sus scrofa largamide A
0.00214
-
-
 Sus scrofa tiglicamide A
0.00216
-
-
 Sus scrofa largamide C methyl ester
0.00223
-
-
 Sus scrofa largamide B methyl ester
0.00294
-
-
 Sus scrofa largamide A methyl ester
0.00699
-
-
 Sus scrofa tiglicamide B
0.00728
-
-
 Sus scrofa tiglicamide C