Literature summary for 3.4.21.36 extracted from

Ay, J.; Hilpert, K.; Krauss, N.; Schneider-Mergener, J.; Hohne, W.
Structure of a hybrid squash inhibitor in complex with porcine pancreatic elastase at 1.8 A resolution (2003), Acta Crystallogr. Sect. D, 59, 247-254.

Search for more literature for 3.4.21.36

Crystallization (Commentary)

Crystallization (Comment)	Organism
structure of a hybrid squash inhibitor, HEI-TOE I, in complex with porcine pancreatic elastase at 1.8 A resolution	Sus scrofa

Inhibitors

Inhibitors	Comment	Organism	Structure
EETI II	trypsin-specific squash inhibitor from Ecballium elaterium	Sus scrofa
HEI-TOE I	hybrid inhibitor from Ecballium elaterium and the optimized binding loop of the third domain of turkey ovomucoid inhibitor	Sus scrofa
OMTKY3	third Kazal-type domain of ovomucoid inhibitor from turkey egg white	Sus scrofa
PACTLEYRC	-	Sus scrofa
PMTLEYR	-	Sus scrofa

Organism

Organism	UniProt	Comment	Textmining
Sus scrofa	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
pancreas	-	Sus scrofa	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
succinyl-Ala-Ala-Ala-4-nitroanilide + H2O	-	Sus scrofa	succinyl-Ala-Ala-Ala + 4-nitroaniline	-	?

Synonyms

Synonyms	Comment	Organism
PPE	-	Sus scrofa

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.000000024	-	OMTKY3	pH 8.5, 25 C	Sus scrofa
0.000098	-	HEI-TOE I	pH 8.5, 25 C	Sus scrofa
0.00067	-	PMTLEYR	pH 8.5, 25 C	Sus scrofa
0.017	-	PACTLEYRC	pH 8.5, 25 C	Sus scrofa
0.082	-	EETI II	pH 8.5, 25 C	Sus scrofa

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)