Activating Compound | Comment | Organism | Structure |
---|---|---|---|
coagulation factor XIIa | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
factor FXII + H2O | Homo sapiens | cleavage between Arg and Val | activated factor XII + ? | - |
? | |
high-molecular-weight kininogen + H2O | Homo sapiens | cleavage between Lys and Arg as wekk as Arg and Ser | bradykinin + fragments of kininogen | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P03952 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
factor FXII + H2O | cleavage between Arg and Val | Homo sapiens | activated factor XII + ? | - |
? | |
high-molecular-weight kininogen + H2O | cleavage between Lys and Arg as wekk as Arg and Ser | Homo sapiens | bradykinin + fragments of kininogen | - |
? | |
additional information | peptides with Pro at P2 are poor substrates | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
KLKb1 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | the activated form of PK is involved in blood pressure regulation | Homo sapiens |