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Literature summary for 3.4.21.34 extracted from
- Modulation of C1-inhibitor and plasma kallikrein activities by type IV collagen (2012), Int. J. Biomater., 2012, 212417.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| C1-inhibitor | - |
Homo sapiens | |
| Type IV collagen | 0.02 mg/ml of collagen causes a slight loss of activity even after 5 hours, whereas with 0.1 mg/ml of collagen, there is an initial rapid decrease of activity to about 40% | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| kininogen + H2O | Homo sapiens | - |
bradykinin + fragments of kininogen | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| kininogen + H2O | - |
Homo sapiens | bradykinin + fragments of kininogen | - |
? | |
| S-2302 + H2O | - |
Homo sapiens | ? | - |
? | |
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