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Literature summary for 3.4.21.34 extracted from

  • Fink, E.; Bhoola, K.D.; Snyman, C.; Neth, P.; Figueroa, C.D.
    Cellular expression of plasma prekallikrein in human tissues (2007), Biol. Chem., 388, 957-963.
    View publication on PubMed
Search for more literature for 3.4.21.34

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular kallikrein Homo sapiens
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intracellular prekallikrein Homo sapiens 5622
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens kallikrein participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation, it has different specific cellular functions dependent on the tissue, overview ?
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P03952
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Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification prekallikrein is synthesized in hepatocytes and other cell types and secreted to the blood, and proteolytically activated to kallikrein Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
breast synthesis of prekallikrein Homo sapiens
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kidney single cells of the distal tubules, synthesis of prekallikrein Homo sapiens
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Langerhans cell synthesis of prekallikrein Homo sapiens
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Leydig cell synthesis of prekallikrein Homo sapiens
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liver plasma prekallikrein is synthesised in hepatocytes and epithalial liver cells, and secreted into the blood Homo sapiens
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oesophagus synthesis of prekallikrein Homo sapiens
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ovary follicular and thecal granulosa cells Homo sapiens
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parotid gland synthesis of prekallikrein Homo sapiens
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plasma kallikrein Homo sapiens
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prostate synthesis of prekallikrein Homo sapiens
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respiratory tract synthesis of prekallikrein Homo sapiens
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skin synthesis of prekallikrein Homo sapiens
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testis interstitial Leydig cells of the testes, synthesis of prekallikrein Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information kallikrein participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation, it has different specific cellular functions dependent on the tissue, overview Homo sapiens ?
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 ?

Synonyms

Synonyms Comment Organism
PPK
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 Homo sapiens