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Literature summary for 3.4.21.27 extracted from

  • Faid, V.; Denguir, N.; Chapuis, V.; Bihoreau, N.; Chevreux, G.
    Site-specific N-glycosylation analysis of human factor XI: Identification of a noncanonical NXC glycosite (2014), Proteomics, 14, 2460-2470.
    View publication on PubMed
Search for more literature for 3.4.21.27

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
68000
-
 2 * 68000, SDS-PAGE Homo sapiens
136100
-
 nonglycosylated, cysteinylated FXI dimer, MALDI-TOF mass spectrometry Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
factor IX + H2O Homo sapiens
-
 factor IXa + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein the enzyme bears five N-glycosylation consensus sites per monomer Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
factor IX + H2O
-
 Homo sapiens factor IXa + ?
-
 ?

Subunits

Subunits Comment Organism
homodimer 2 * 68000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
factor XI
-
 Homo sapiens
FXI
-
 Homo sapiens

General Information

General Information Comment Organism
malfunction enzyme deficiency results in bleeding diathesis referred to as hemophilia C Homo sapiens
physiological function the enzyme is involved in the coagulation cascade Homo sapiens