Cloned (Comment) | Organism |
---|---|
expressed in Pichia pastoris | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
in complex with inhibitors, hanging drop vapor diffusion method, using 0.1 M citrate pH 4.7-5.2, 20-26% (w/v) PEG 4K | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
C500S | inactive | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N-[(2S)-1-([2-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]ethyl]amino)-1-oxo-3-phenylpropan-2-yl]-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-7-carboxamide | - |
Homo sapiens | |
[4-[(N-[3-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]propanoyl]-L-phenylalanyl)amino]phenyl]acetic acid | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
factor IX + H2O | Homo sapiens | - |
factor IXa + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P03951 | - |
- |
Purification (Comment) | Organism |
---|---|
Zn2+-chelating Sepharose column chromatography and SP Sepharose column chromatography | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
factor IX + H2O | - |
Homo sapiens | factor IXa + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
coagulation factor XI | - |
Homo sapiens |
FXIa | - |
Homo sapiens |