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Literature summary for 3.4.21.27 extracted from
- The role of thrombin activatable fibrinolysis inhibitor and factor XI in platelet-mediated fibrinolysis resistance: A thromboelastographic study in whole blood (2011), J. Thromb. Haemost., 9, 154-162.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Factor XII | - |
Homo sapiens | |
| additional information | in blood challenged with low concentrations of tissue factor, factor XI can be activated independently of factor XII | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| factor IX + H2O | - |
Homo sapiens | activated factor IX + ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| factor XIa | - |
Homo sapiens |
| FXIa | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | factor XIa plays its major role in promoting late thrombin formation (i.e. the thrombin required for thrombin activatable fibrinolysis inhibitor-mediated inhibition of fibrinolysis) | Homo sapiens |
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