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Literature summary for 3.4.21.27 extracted from

  • Singh, A.; Harnett, M.J.; Connors, J.M.; Camann, W.R.
    Factor XI deficiency and obstetrical anesthesia (2009), Anesth. Analg., 108, 1882-1885.
    View publication on PubMed

Application

Application Comment Organism
medicine diagnosis of FXI deficiency may be considered in patients with delayed postoperative bleeding and prolonged activated partial thromboplastin time, especially in a demographically high-risk population, such as Ashkenazi Jews. Women with severe FXI deficiency and prolonged activated partial thromboplastin time can be managed with fresh frozen plasma transfusion before neuraxial anesthesia Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P03951
-
-

Synonyms

Synonyms Comment Organism
factor XI
-
Homo sapiens
FXI
-
Homo sapiens

General Information

General Information Comment Organism
malfunction activated partial thromboplastin time is abnormal in all cases with severe or moderate FXI deficiency. FXI deficiency is not an absolute contraindication to neuraxial anesthesia Homo sapiens