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Literature summary for 3.4.21.21 extracted from
- Thermal effects on an enzymatically latent conformation of coagulation factor VIIa (1999), Eur. J. Biochem., 261, 124-129.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| tissue factor | increases cleavage of Ile-Pro-Arg-p-nitroanilide | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Ile-Pro-Arg-p-nitroanilide + H2O | - |
Homo sapiens | ? | - |
? |  |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 15 | - |
cleavage of Ile-Pro-Arg-p-nitroanilide | Homo sapiens |
| 30 | - |
cleavage of Ile-Pro-Arg-p-nitroanilide, in presence of tissue factor | Homo sapiens |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 5 | 40 | 5°C: about 90% of maximal activity, 40°C: about 50% of maximal activity, cleavage of Ile-Pro-Arg-p-nitroanilide | Homo sapiens |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 58 | - |
heat inactivation is fully reversible up to 15 min | Homo sapiens |
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Release 2023.1 (January 2023)
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