Activating Compound | Comment | Organism | Structure |
---|---|---|---|
tissue factor | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Eph tyrosine kinase receptor EphA2 + H2O | Homo sapiens | cleavage site at the Arg159-His160 bond | ? | - |
? | |
Eph tyrosine kinase receptor EphB2 + H2O | Homo sapiens | cleavage site at the Arg159-His160 bond | ? | - |
? | |
protease-activated receptor 2 + H2O | Homo sapiens | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Eph tyrosine kinase receptor EphA2 + H2O | cleavage site at the Arg159-His160 bond | Homo sapiens | ? | - |
? | |
Eph tyrosine kinase receptor EphB2 + H2O | cleavage site at the Arg159-His160 bond | Homo sapiens | ? | - |
? | |
protease-activated receptor 2 + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
factor VIIa | - |
Homo sapiens |
FVIIa | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | FVIIa causes potentiation of cell repulsion by the Eph tyrosine kinase receptor EphB2 ligand ephrin-B1, demonstrating a proteolytical event to control Eph-mediated cell segregation | Homo sapiens |