Inhibitors | Comment | Organism | Structure |
---|---|---|---|
serpinB6 | is a physiologically relevant inhibitor of hK8 in skin. SerpinB6 protects the intracellular compartment of keratinocytes from ectopic hK8 | Homo sapiens | |
serpinB6 | - |
Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | distributed in keratinocytes in the stratum spinosum and granulosum | Homo sapiens | 5737 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
35000 | - |
immunoblotting | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
keratinocyte | hK8 and serpinB6 are co-expressed in differentiated primary human keratinocytes | Homo sapiens | - |
keratinocyte | interaction between murine serpinB6 and mK8 is at least 10fold faster than that observed for serpinB6 and hK8 | Mus musculus | - |
skin | - |
Mus musculus | - |
skin | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Boc-Val-Pro-Arg-4-methylcoumaryl-7-amide + H2O | - |
Homo sapiens | Boc-Val-Pro-Arg + 7-amino-4-methylcoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
hK8 | - |
Homo sapiens |
kallikrein-8 | - |
Mus musculus |
kallikrein-8 | - |
Homo sapiens |
KLK8 | - |
Mus musculus |
KLK8 | - |
Homo sapiens |
mK8 | - |
Mus musculus |
neuropsin | - |
Mus musculus |
neuropsin | - |
Homo sapiens |
PRSS19 | - |
Mus musculus |
PRSS19 | - |
Homo sapiens |