Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | decanoyl-RVKR-chloromethylketone does not affect SKI-1-mediated processing; decanoyl-RVKR-chloromethylketone inhibition is selective to furin/PCs and does not affect SKI-1-mediated processing | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | SW-13 cell, infected with crimean-Congo hemorrhagic fever virus | Homo sapiens | - |
additional information | SW-13 cell | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Crimean Congo hemorrhagic fever virus glycoprotein + H2O | posttranslational cleavage by furin/PC-mediated processing at its N-terminus at RSKR247 and by SKI-1 at its C-terminus at RRLL519 | Homo sapiens | ? | - |
? | |
glycoprotein precursor Gc + H2O | - |
Homo sapiens | ? | - |
? | |
glycoprotein precursor Gn + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SKI-1 | - |
Homo sapiens |