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Literature summary for 3.4.21.109 extracted from

  • Ganesan, R.; Eigenbrot, C.; Kirchhofer, D.
    Structural and mechanistic insight into how antibodies inhibit serine proteases (2010), Biochem. J., 430, 179-189.
    View publication on PubMed
Search for more literature for 3.4.21.109

Inhibitors

Inhibitors Comment Organism Structure
additional information the enzyme is competitively inhibited by the anti-MT-SP1 antibody FabE2 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane type II transmembrane serine protease Homo sapiens 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the P1 residue for MT-SP1 substrates is either arginine or lysine ?
-
 ?
pro-hepatocyte growth factor + H2O Homo sapiens
-
 ?
-
 ?
pro-urokinase-type plasminogen activator + H2O Homo sapiens
-
 ?
-
 ?
prostasin + H2O Homo sapiens
-
 ?
-
 ?
protease activated receptor 2 + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the P1 residue for MT-SP1 substrates is either arginine or lysine Homo sapiens ?
-
 ?
pro-hepatocyte growth factor + H2O
-
 Homo sapiens ?
-
 ?
pro-urokinase-type plasminogen activator + H2O
-
 Homo sapiens ?
-
 ?
prostasin + H2O
-
 Homo sapiens ?
-
 ?
protease activated receptor 2 + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
MT-SP1
-
 Homo sapiens