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Literature summary for 3.4.21.108 extracted from

  • Luo, F.; Wei, L.; Sun, C.; Chen, X.; Wang, T.; Li, Y.; Liu, Z.; Chen, Z.; Xu, P.
    HtrA2/Omi is involved in 6-OHDA-induced endoplasmic reticulum stress in SH-SY5Y cells (2012), J. Mol. Neurosci., 47, 120-127.
    View publication on PubMed
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Organism

Organism UniProt Comment Textmining
Homo sapiens O43464
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Source Tissue

Source Tissue Comment Organism Textmining
SH-SY5Y cell
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 Homo sapiens
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Synonyms

Synonyms Comment Organism
HtrA2/Omi
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 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens the expression level of HtrA2/Omi decreases with endoplasmic reticulum stress induction in 6-hydroxydopamine-treated SH-SY5Y cells down

General Information

General Information Comment Organism
physiological function silencing endogenous expression of HtrA2/Omi with siRNA results in aggregated endoplasmic reticulum stress and cell death. The expression level of HtrA2/Omi decreases with endoplasmic reticulum stress induction in 6-hydroxydopamine-treated SH-SY5Y cells Homo sapiens