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Literature summary for 3.4.21.108 extracted from

  • Yun, J.; Cao, J.H.; Dodson, M.W.; Clark, I.E.; Kapahi, P.; Chowdhury, R.B.; Guo, M.
    Loss-of-function analysis suggests that Omi/HtrA2 is not an essential component of the PINK1/PARKIN pathway in vivo (2008), J. Neurosci., 28, 14500-14510.
    View publication on PubMed
Search for more literature for 3.4.21.108

Application

Application Comment Organism
medicine mutations in the OMI/HTRA2 gene are linked to Parkinsons disease Drosophila melanogaster

Cloned(Commentary)

Cloned (Comment) Organism
into the vectors pUASt and pTMR Drosophila melanogaster

Protein Variants

Protein Variants Comment Organism
G363S Drosophila Omi mutant analogous to human Omi/HtrA2 mutation G399S Drosophila melanogaster
S236C Drosophila Omi mutant analogous to human Omi/HtrA2 mutation S276C Drosophila melanogaster
S266A Drosophila Omi mutant analogous to human Omi/HtrA2 mutation S306A Drosophila melanogaster
S364A Drosophila Omi mutant analogous to human Omi/HtrA2 mutation S400A Drosophila melanogaster

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol released into the cytosol upon apoptotic stimuli Drosophila melanogaster 5829
-
mitochondrial intermembrane space
-
 Drosophila melanogaster 5758
-
mitochondrion
-
 Drosophila melanogaster 5739
-

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster Q9VFJ3
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein
-
 Drosophila melanogaster

Source Tissue

Source Tissue Comment Organism Textmining
eye
-
 Drosophila melanogaster
-

Synonyms

Synonyms Comment Organism
Omi/HtrA2
-
 Drosophila melanogaster
serine protease
-
 Drosophila melanogaster