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Literature summary for 3.4.21.108 extracted from

  • Sekine, K.; Hao, Y.; Suzuki, Y.; Takahashi, R.; Tsuruo, T.; Naito, M.
    HtrA2 cleaves Apollon and induces cell death by IAP-binding motif in Apollon-deficient cells (2005), Biochem. Biophys. Res. Commun., 330, 279-285.
    View publication on PubMed
Search for more literature for 3.4.21.108

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Homo sapiens 5739
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Apollon + H2O HtrA2 cleaves Apollon, a huge inhibitor of apoptosis protein, with its serine protease activity, conversely, Apollon ubiquitylates and facilitates proteasomal degradation of HtrA2, thus both downregulate each other Homo sapiens ?
-
 ?
casein + H2O
-
 Homo sapiens ?
-
 ?
X-linked inhibitor of apoptosis protein + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
HtrA2
-
 Homo sapiens