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Literature summary for 3.4.21.108 extracted from

  • Li, W.; Srinivasula, S.M.; Chai, J.; Li, P.; Wu, J.W.; Zhang, Z.; Alnemri, E.S.; Shi, Y.
    Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi (2002), Nat. Struct. Biol., 9, 436-441.
    View publication on PubMed
Search for more literature for 3.4.21.108

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging drop vapor diffusion method Mammalia

Protein Variants

Protein Variants Comment Organism
F149D comparable level of binding to XIAP as the wild type-enzyme Mammalia
S306A comparable level of binding to XIAP as the wild type-enzyme Mammalia

Localization

Localization Comment Organism GeneOntology No. Textmining

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
36000
-
 3 * 36000, gel filtration Mammalia
110000
-
 gel filtration Mammalia

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mammalia role in apoptosis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mammalia
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-casein + H2O
-
 Mammalia ?
-
 ?
additional information role in apoptosis Mammalia ?
-
 ?

Subunits

Subunits Comment Organism
trimer 3 * 36000, gel filtration Mammalia

Synonyms

Synonyms Comment Organism
HtrA2/Omi
-
 Mammalia