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Literature summary for 3.4.21.108 extracted from

  • Yang, Q.H.; Church-Hajduk, R.; Ren, J.; Newton, M.L.; Du, C.
    Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis (2003), Genes Dev., 17, 1487-1496.
    View publication on PubMed
Search for more literature for 3.4.21.108

Cloned(Commentary)

Cloned (Comment) Organism
-
 Mammalia

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mammalia promotes apoptosis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mammalia
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mammalia

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-casein + H2O
-
 Mammalia ?
-
 ?
beta-casein + H2O
-
 Mammalia ?
-
 ?
glycprotein alpha1 acid + H2O
-
 Mammalia ?
-
 ?
hyaluronidase + H2O
-
 Mammalia ?
-
 ?
inhibitor of apoptosis + H2O enzyme cleaves various IAPs Mammalia ?
-
 ?
Livin alpha + H2O
-
 Mammalia ?
-
 ?
Livin beta
-
 Mammalia ?
-
 ?
additional information promotes apoptosis Mammalia ?
-
 ?
protein cIAP1 + H2O best substrate, preferred cleavage sites are after Thr4, Asn133 and Leu161 Mammalia ?
-
 ?
protein cIAP2 + H2O
-
 Mammalia ?
-
 ?
protein DIAP1 + H2O
-
 Mammalia ?
-
 ?
protein XIAP + H2O
-
 Mammalia ?
-
 ?

Synonyms

Synonyms Comment Organism
HtrA2/Omi
-
 Mammalia

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Mammalia