Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O00187 | - |
- |
Subunits | Comment | Organism |
---|---|---|
More | recombinant CUB1-EGF-CUB2 regions of MASP-2 show a slow and incomplete dissociation of dimer by EDTA and appearance of high molecular weight aggregates | Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | mannan-binding lectin-associated serine proteases MASP-1 and MASP-2 can readily form heterodimers after dissociation and re-association, however, in thepresence of Ca2+ exchange of subunits is slow between the homodimers. Modeling of isoforms MASP-1:MASP-3 heterodimer formation indicates that subunits of these proteins are readily exchanged even in the presence of Ca2+ | Homo sapiens |