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Literature summary for 3.4.21.104 extracted from

  • Mayilyan, K.R.; Arnold, J.N.; Presanis, J.S.; Soghoyan, A.F.; Sim, R.B.
    Increased complement classical and mannan-binding lectin pathway activities in schizophrenia (2006), Neurosci. Lett., 404, 336-341.
    View publication on PubMed
Search for more literature for 3.4.21.104

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
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 Homo sapiens
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-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme binds to the mannan-binding lectin, the complex activates the lectin pathway of the complement system, increased activity of MBL-bound MASP-2 and MASP-2-mediated complement activation in schizophrenia, while the levels of MASP-1 and unbound MBL are similar to healthy persons' levels, overview ?
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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 healthy individuals and schizophrenia patients
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Source Tissue

Source Tissue Comment Organism Textmining
blood
-
 Homo sapiens
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 lectin pathway of the complement system component activities in healthy individuals and schizophrenia patients, overview Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme binds to the mannan-binding lectin, the complex activates the lectin pathway of the complement system, increased activity of MBL-bound MASP-2 and MASP-2-mediated complement activation in schizophrenia, while the levels of MASP-1 and unbound MBL are similar to healthy persons' levels, overview Homo sapiens ?
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 ?

Synonyms

Synonyms Comment Organism
MASP-2
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 Homo sapiens