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Literature summary for 3.4.21.104 extracted from

  • Sorensen, G.L.; Petersen, I.; Thiel, S.; Fenger, M.; Christensen, K.; Kyvik, K.O.; S?rensen, T.I.; Holmskov, U.; Jensenius, J.C.
    Genetic influences on mannan-binding lectin (MBL) and mannan-binding lectin associated serine protease-2 (MASP-2) activity (2007), Genet. Epidemiol., 31, 31-41.
    View publication on PubMed
Search for more literature for 3.4.21.104

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
complement component C4 + H2O Homo sapiens
-
 ?
-
 ?
additional information Homo sapiens the enzyme binds to the mannan-binding lectin, the complex activates the lectin pathway of the complement system, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 Danish adult twins, monozygotic and dizygotic twin pairs
-

Source Tissue

Source Tissue Comment Organism Textmining
serum distribution in the investigated twin sample population, modeling, overview Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
complement component C4 + H2O
-
 Homo sapiens ?
-
 ?
complement component C4 + H2O determination of C4b deposition on a mannan surface Homo sapiens ?
-
 ?
additional information the enzyme binds to the mannan-binding lectin, the complex activates the lectin pathway of the complement system, overview Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
Mannan-binding lectin associated serine protease-2
-
 Homo sapiens
MASP-2
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Homo sapiens