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Literature summary for 3.4.21.104 extracted from

  • Moller-Kristensen, M.; Jensenius, J.C.; Jensen, L.; Thielens, N.; Rossi, V.; Arlaud, G.; Thiel, S.
    Levels of mannan-binding lectin-associated serine protease-2 in healthy individuals (2003), J. Immunol. Methods, 282, 159-167.
    View publication on PubMed
Search for more literature for 3.4.21.104

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
50000
-
 x * 75000, full-length proenzyme, SDS-PAGE, x * 50000, A-chain of the enzyme, SDS-PAGE Homo sapiens
75000
-
 x * 75000, full-length proenzyme, SDS-PAGE, x * 50000, A-chain of the enzyme, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
complement component C2 + H2O Homo sapiens involved in lectin pathway being part of the innate immune system providing a first line of defense against infections by activation of the complement cascade 2 fragments of complement component C2
-
 ?
complement component C4 + H2O Homo sapiens involved in lectin pathway being part of the innate immune system providing a first line of defense against infections by activation of the complement cascade 2 fragments of complement C4
-
 ?
additional information Homo sapiens enzyme in serum is complexed with mannan-binding lectin MBL and ficolins ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information enzyme content in plasma of blood donors during 1 year, overview Homo sapiens
-
plasma
-
 Homo sapiens
-
serum
-
 Homo sapiens
-

Storage Stability

Storage Stability Organism
-20°C, 4°C, and room temperature, 30 days, stable at Homo sapiens
37°C, loss of about 95% activity within 30 days Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
complement component C2 + H2O
-
 Homo sapiens 2 fragments of complement component C2
-
 ?
complement component C2 + H2O involved in lectin pathway being part of the innate immune system providing a first line of defense against infections by activation of the complement cascade Homo sapiens 2 fragments of complement component C2
-
 ?
complement component C4 + H2O
-
 Homo sapiens 2 fragments of complement C4
-
 ?
complement component C4 + H2O involved in lectin pathway being part of the innate immune system providing a first line of defense against infections by activation of the complement cascade Homo sapiens 2 fragments of complement C4
-
 ?
additional information enzyme in serum is complexed with mannan-binding lectin MBL and ficolins Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
? x * 75000, full-length proenzyme, SDS-PAGE, x * 50000, A-chain of the enzyme, SDS-PAGE Homo sapiens
More enzyme in serum is complexed with mannan-binding lectin MBL and ficolins Homo sapiens

Synonyms

Synonyms Comment Organism
MASP-2
-
 Homo sapiens
MBP-associated serine protease 2
-
 Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Homo sapiens