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Literature summary for 3.4.19.3 extracted from
- Some properties of synaptosomal membrane-bound pyroglutamate aminopeptidase from guinea-pig brain (1985), Biochem. Soc. Trans., 3, 485-487.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | weak inhibition | Cavia porcellus |  |
| Cd2+ | - |
Bacillus amyloliquefaciens | |
| Cd2+ | - |
Cavia porcellus | |
| Chelating agents | strong | Cavia porcellus | |
| Cu2+ | - |
Bacillus amyloliquefaciens | |
| Cu2+ | - |
Cavia porcellus | |
| Fe3+ | weak inhibition | Cavia porcellus | |
| Mn2+ | weak inhibition | Cavia porcellus | |
| Zn2+ | - |
Cavia porcellus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | bound to | Cavia porcellus | 16020 | - |
| membrane | synaptosomal | Cavia porcellus | 16020 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus amyloliquefaciens | - |
- |
- |
| Cavia porcellus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Cavia porcellus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| thyroliberin + H2O | removes the N-terminal pyroglutamic acid | Cavia porcellus | pyroglutamate + His-Pro-NH2 | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
- |
Cavia porcellus |
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