Inhibitors | Comment | Organism | Structure |
---|---|---|---|
serine borate | competitive, 8fold less effective as an inhibitor of isoform GGT5 than of GGT1; competitive, 8fold less effective as an inhibitor of isoform GGT5 than of GGT1 | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0088 | - |
oxidized glutathione | pH 7.4, 37°C | Homo sapiens | |
0.0102 | - |
leukotriene C4 | pH 7.4, 37°C | Homo sapiens | |
0.0105 | - |
reduced glutathione | pH 7.4, 37°C | Homo sapiens | |
0.0106 | - |
reduced glutathione | pH 7.4, 37°C | Homo sapiens | |
0.0108 | - |
leukotriene C4 | pH 7.4, 37°C | Homo sapiens | |
0.0131 | - |
S-(4-nitro-benzyl)glutathione | pH 7.4, 37°C | Homo sapiens | |
0.0148 | - |
S-(4-nitro-benzyl)glutathione | pH 7.4, 37°C | Homo sapiens | |
0.0182 | - |
S-Methylglutathione | pH 7.4, 37°C | Homo sapiens | |
0.0334 | - |
gamma-glutamyl L-leucine | pH 7.4, 37°C | Homo sapiens | |
0.0346 | - |
glutathione sulfonic acid | pH 7.4, 37°C | Homo sapiens | |
0.0426 | - |
oxidized glutathione | pH 7.4, 37°C | Homo sapiens | |
0.0751 | - |
glutathione sulfonic acid | pH 7.4, 37°C | Homo sapiens | |
0.099 | - |
S-Methylglutathione | pH 7.4, 37°C | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P19440 | - |
- |
Homo sapiens | P36269 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
gamma-glutamyl L-leucine + H2O | - |
Homo sapiens | L-leucine + L-glutamate | - |
? | |
glutathione sulfonic acid + H2O | - |
Homo sapiens | ? + L-glutamate | - |
? | |
leukotriene C4 + H2O | - |
Homo sapiens | ? | - |
? | |
additional information | no substrate: gamma-glutamyl L-leucine | Homo sapiens | ? | - |
? | |
additional information | protein additionally has EC 2.3.2.2, gamma-glutamyltransferase activity | Homo sapiens | ? | - |
? | |
oxidized glutathione + H2O | - |
Homo sapiens | ? + L-glutamate | - |
? | |
reduced glutathione + H2O | - |
Homo sapiens | L-cysteinylglycine + L-glutamate | - |
? | |
S-(4-nitro-benzyl)glutathione + H2O | - |
Homo sapiens | S-(4-nitro-benzyl)-L-cysteinylglycine + L-glutamate | - |
? | |
S-methylglutathione + H2O | - |
Homo sapiens | S-methyl-L-cysteinylglycine + L-glutamate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
gamma-glutamyl transpeptidase | - |
Homo sapiens |
GGT1 | - |
Homo sapiens |
GGT5 | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
4.2 | - |
serine borate | pH 7.4, 37°C | Homo sapiens |