KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00004 | - |
ubiquitin-7-amido-4-methylcoumarin | with UCH-L1 | synthetic construct | |
0.00008 | - |
ubiquitin-AW | with UCH-L1 | synthetic construct | |
0.0001 | - |
ubiquitin-W-R42A | with UCH-L1 | synthetic construct | |
0.0001 | - |
ubiquitin-W-G75A | with UCH-L1 | synthetic construct | |
0.0001 | - |
ubiquitin-W-R42A | with UCH-L3 | synthetic construct | |
0.00013 | - |
ubiquitin-W | with UCH-L1 | synthetic construct | |
0.0002 | - |
ubiquitin-W-R74A | with UCH-L1 | synthetic construct | |
0.0003 | - |
ubiquitin-W-K48A | with UCH-L1 | synthetic construct | |
0.00031 | - |
ubiquitin-W-I44A | with UCH-L1 | synthetic construct | |
0.0004 | - |
ubiquitin-W-K63A | with UCH-L1 | synthetic construct | |
0.0004 | - |
ubiquitin-W-I44A | with UCH-L3 | synthetic construct | |
0.0004 | - |
ubiquitin-W-G75A | with UCH-L3 | synthetic construct | |
0.00045 | - |
ubiquitin-WA | with UCH-L1 | synthetic construct | |
0.0005 | - |
ubiquitin-W-H68A | with UCH-L1 | synthetic construct | |
0.0005 | - |
ubiquitin-W-H68A | with UCH-L3 | synthetic construct | |
0.0006 | - |
ubiquitin-W-V70A | with UCH-L1 | synthetic construct | |
0.0006 | - |
ubiquitin-W-R72A | with UCH-L1 | synthetic construct | |
0.0007 | - |
ubiquitin-W-K48A | with UCH-L3 | synthetic construct | |
0.0008 | - |
ubiquitin-W-K63A | with UCH-L3 | synthetic construct | |
0.0009 | - |
ubiquitin-W-K6A | with UCH-L1 | synthetic construct | |
0.0011 | - |
ubiquitin-W-K11A | with UCH-L1 | synthetic construct | |
0.0011 | - |
ubiquitin-W-G76A | with UCH-L3 | synthetic construct | |
0.0011 | - |
ubiquitin-W-V70A | with UCH-L3 | synthetic construct | |
0.0014 | - |
ubiquitin-W-K6A | with UCH-L3 | synthetic construct | |
0.0019 | - |
ubiquitin-W-R72A | with UCH-L3 | synthetic construct | |
0.002 | - |
ubiquitin-W-G76A | with UCH-L1 | synthetic construct | |
0.0023 | - |
ubiquitin-W-K11A | with UCH-L3 | synthetic construct | |
0.0045 | - |
ubiquitin-W-R74A | with UCH-L3 | synthetic construct | |
0.0058 | - |
ubiquitin-W-L73A | with UCH-L1 | synthetic construct | |
0.008 | - |
ubiquitin-W-L71A | with UCH-L1 | synthetic construct | |
0.0104 | - |
ubiquitin-W-L73A | with UCH-L3 | synthetic construct | |
0.0198 | - |
ubiquitin-W-L71A | with UCH-L3 | synthetic construct | |
0.0282 | - |
ubiquitin-W-L8A | with UCH-L3 | synthetic construct | |
0.03 | - |
ubiquitin-W-L8A | with UCH-L1 | synthetic construct |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
synthetic construct | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ubiquitin-7-amido-4-methylcoumarin + H2O | - |
synthetic construct | ubiquitin + 7-amino-4-methylcoumarin | - |
? | |
ubiquitin-7-amido-4-methylcoumarin + H2O | - |
synthetic construct | ? | - |
? | |
ubiquitin-AW + H2O | - |
synthetic construct | ? | - |
? | |
ubiquitin-AW + H2O | poor substrate for UCH-L1 | synthetic construct | ? | - |
? | |
ubiquitin-W + H2O | - |
synthetic construct | ? | - |
? | |
ubiquitin-W + H2O | competent substrate for both UCH-L1 and UCH-L3 | synthetic construct | ? | - |
? | |
ubiquitin-W-G75A + H2O | - |
synthetic construct | ? | - |
? | |
ubiquitin-W-G76A + H2O | - |
synthetic construct | ? | - |
? | |
ubiquitin-W-H68A + H2O | - |
synthetic construct | ? | - |
? | |
ubiquitin-W-I44A + H2O | - |
synthetic construct | ? | - |
? | |
ubiquitin-W-K11A + H2O | - |
synthetic construct | ? | - |
? | |
ubiquitin-W-K48A + H2O | - |
synthetic construct | ? | - |
? | |
ubiquitin-W-K63A + H2O | - |
synthetic construct | ? | - |
? | |
ubiquitin-W-K6A + H2O | - |
synthetic construct | ? | - |
? | |
ubiquitin-W-L71A + H2O | - |
synthetic construct | ? | - |
? | |
ubiquitin-W-L73A + H2O | - |
synthetic construct | ? | - |
? | |
ubiquitin-W-L8A + H2O | - |
synthetic construct | ? | - |
? | |
ubiquitin-W-R42A + H2O | - |
synthetic construct | ? | - |
? | |
ubiquitin-W-R72A + H2O | - |
synthetic construct | ? | - |
? | |
ubiquitin-W-R74A + H2O | - |
synthetic construct | ? | - |
? | |
ubiquitin-W-V70A + H2O | - |
synthetic construct | ? | - |
? | |
ubiquitin-WA + H2O | - |
synthetic construct | ? | - |
? | |
ubiquitin-WA + H2O | poor substrate for UCH-L1 | synthetic construct | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ubiquitin carboxy-terminal hydrolase L1 | - |
synthetic construct |
UCH-L1 | - |
synthetic construct |
UCH-L3 | - |
synthetic construct |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0001 | - |
ubiquitin-AW | with UCH-L1 | synthetic construct | |
0.0005 | - |
ubiquitin-WA | with UCH-L1 | synthetic construct | |
0.0011 | - |
ubiquitin-W-G76A | with UCH-L1 | synthetic construct | |
0.01 | - |
ubiquitin-W-L73A | with UCH-L1 | synthetic construct | |
0.01 | - |
ubiquitin-W-R74A | with UCH-L1 | synthetic construct | |
0.01 | - |
ubiquitin-W-G75A | with UCH-L1 | synthetic construct | |
0.02 | - |
ubiquitin-W-R42A | with UCH-L1 | synthetic construct | |
0.02 | - |
ubiquitin-7-amido-4-methylcoumarin | with UCH-L1 | synthetic construct | |
0.03 | - |
ubiquitin-W-K6A | with UCH-L1 | synthetic construct | |
0.03 | - |
ubiquitin-W-K11A | with UCH-L1 | synthetic construct | |
0.03 | - |
ubiquitin-W-K63A | with UCH-L1 | synthetic construct | |
0.03 | - |
ubiquitin-W-L71A | with UCH-L1 | synthetic construct | |
0.03 | - |
ubiquitin-W-R72A | with UCH-L1 | synthetic construct | |
0.03 | - |
ubiquitin-W | with UCH-L1 | synthetic construct | |
0.04 | - |
ubiquitin-W-K48A | with UCH-L1 | synthetic construct | |
0.05 | - |
ubiquitin-W-V70A | with UCH-L1 | synthetic construct | |
0.06 | - |
ubiquitin-W-H68A | with UCH-L1 | synthetic construct | |
0.09 | - |
ubiquitin-W-I44A | with UCH-L1 | synthetic construct | |
0.2 | - |
ubiquitin-W-R42A | with UCH-L3 | synthetic construct | |
0.3 | - |
ubiquitin-W-R74A | with UCH-L3 | synthetic construct | |
1.6 | - |
ubiquitin-W-I44A | with UCH-L3 | synthetic construct | |
1.7 | - |
ubiquitin-W-G76A | with UCH-L3 | synthetic construct | |
2.4 | - |
ubiquitin-W-K48A | with UCH-L3 | synthetic construct | |
2.4 | - |
ubiquitin-W-K63A | with UCH-L3 | synthetic construct | |
2.9 | - |
ubiquitin-W-G75A | with UCH-L3 | synthetic construct | |
3.4 | - |
ubiquitin-W-K11A | with UCH-L3 | synthetic construct | |
4 | - |
ubiquitin-W-K6A | with UCH-L3 | synthetic construct | |
4.4 | - |
ubiquitin-W-R72A | with UCH-L3 | synthetic construct | |
4.6 | - |
ubiquitin-W-H68A | with UCH-L3 | synthetic construct | |
5.7 | - |
ubiquitin-W-L73A | with UCH-L3 | synthetic construct | |
6.6 | - |
ubiquitin-W-L8A | with UCH-L3 | synthetic construct | |
6.7 | - |
ubiquitin-W-V70A | with UCH-L3 | synthetic construct | |
9.2 | - |
ubiquitin-W-L71A | with UCH-L3 | synthetic construct |