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Literature summary for 3.4.19.12 extracted from

  • Wicks, S.J.; Haros, K.; Maillard, M.; Song, L.; Cohen, R.E.; Dijke, P.T.; Chantry, A.
    The deubiquitinating enzyme UCH37 interacts with Smads and regulates TGF-beta signalling (2005), Oncogene, 24, 8080-8084.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
type I TGF-beta receptor + H2O Homo sapiens UCH37 deubiquitinates and stabilizes type I TGF-beta receptor. Overexpression of UCH37 upregulates TGF-beta-dependent transcription ?
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9Y5K5
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
type I TGF-beta receptor + H2O UCH37 deubiquitinates and stabilizes type I TGF-beta receptor. Overexpression of UCH37 upregulates TGF-beta-dependent transcription Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
Ubiquitin C-terminal hydrolase UCH37
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Homo sapiens
UCH37
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Homo sapiens