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Literature summary for 3.4.17.6 extracted from

  • Iwaya, M.; Strominger, J.L.
    Simultaneous deletion of D-alanine carboxypeptidase IB-C and penicillin-binding component IV in a mutant of Escherichia coli K12 (1977), Proc. Natl. Acad. Sci. USA, 74, 2980-2984.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine possible penicillin target Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
additional information simultaneous mutational deletion of enzyme activity and penicillin-binding component IV Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
mutant K12 with decreased activity
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
activities per g wet weight 10fold higher in wild-type than in K12 cells Escherichia coli