Literature summary for 3.4.17.23 extracted from

Zhang, H.; Penninger, J.; Li, Y.; Zhong, N.; Slutsky, A.
Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor molecular mechanisms and potential therapeutic target (2020), Intensive Care Med., 46, 586-590.

Search for more literature for 3.4.17.23

Application

Application	Comment	Organism
medicine	potential therapeutic approach to ACE2-mediated COVID-19. Treatment with a soluble form of ACE2 may exert dual functions, slow viral entry into cells and hence viral spread and protect the lung from injury	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9BYF1	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
alveolar cell type II	83% of ACE2-expressing cells are alveolar epithelial type II cells	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
ACE2	-	Homo sapiens

General Information

General Information	Comment	Organism
drug target	potential therapeutic approach to ACE2-mediated COVID-19. Treatment with a soluble form of ACE2 may exert dual functions, slow viral entry into cells and hence viral spread and protect the lung from injury	Homo sapiens
physiological function	the SARS-CoV-2 spike protein directly binds with the host cell surface ACE2 receptor facilitating virus entry and replication	Homo sapiens

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Release 2023.1 (January 2023)