Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of several transgenic linages with differential virological and immunological outcome of severe acute respiratory syndrome coronavirus infection in susceptible and resistant transgenic mice expressing human ACE2, overview. Transgenic lineages AC70 and AC22, representing those susceptible and resistant to the lethal SARS-CoV infection, respectively, are both permissive to SARS-CoV infection, causing elevated secretion of many inflammatory mediators within the lungs and brains, viral infection appears to be more intense in AC70 than in AC22 mice, especially in the brain, differential SARS-CoV-induced morbidity and mortality between AC70 and AC22 mice, overview | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
epithelium | - |
Homo sapiens | - |
lung | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
ACE2 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | angiotensin-converting enzyme 2 is the receptor for severe acute respiratory syndrome coronavirus, SARS-CoV | Homo sapiens |