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Literature summary for 3.4.17.23 extracted from

  • Garabelli, P.J.; Modrall, J.G.; Penninger, J.M.; Ferrario, C.M.; Chappell, M.C.
    Distinct roles for angiotensin-converting enzyme 2 and carboxypeptidase A in the processing of angiotensins within the murine heart (2008), Exp. Physiol., 93, 613-621.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
benzylsuccinate essentially abolishes the formation of Ang(1-9) by ACE2 Mus musculus
MLN-4760 total inhibition at 0.01 mM Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Mus musculus 16020
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
angiotensin I + H2O
-
Mus musculus angiotensin-(1-9) + Leu
-
?
angiotensin II + H2O
-
Mus musculus angiotensin-(1-7) + Phe
-
?

Synonyms

Synonyms Comment Organism
ACE2
-
Mus musculus