Literature summary for 3.4.17.23 extracted from

Zisman, L.S.; Keller, R.S.; Weaver, B.; Lin, Q.; Speth, R.; Bristow, M.R.; Canver, C.C.
Increased angiotensin-(1-7)-forming activity in failing human heart ventricles: evidence for upregulation of the angiotensin-converting enzyme homologue ACE2 (2003), Circulation, 108, 1707-1712.

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Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	no inhibition by enalaprilat	Homo sapiens
N-[(1S)-1-carboxy-3-methylbutyl]-3-(3,5-dichlorobenzyl)-L-histidine	enzyme-specific inhibitor	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Homo sapiens	16020	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9BYF1	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
angiotensin I + H2O	-	Homo sapiens	angiotensin-(1-9) + Leu	-	?
angiotensin II + H2O	preferred substrate	Homo sapiens	angiotensin-(1-7) + Phe	-	?

Synonyms

Synonyms	Comment	Organism
angiotensinase	-	Homo sapiens

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Release 2023.1 (January 2023)