Application | Comment | Organism |
---|---|---|
medicine | glutamate carboxypeptidase II may represent a viable therapeutic target for intervention on psychiatric disease | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(S)-2-(3-((S)-1-carboxy-2-(4-hydroxy-3-iodophenyl)ethyl)ureido)pentanedioic acid | DCIT | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Homo sapiens | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-acetyl-L-aspartyl-L-glutamate + H2O | Homo sapiens | - |
N-acetyl-L-aspartate + L-glutamate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
entorhinal cortex | - |
Homo sapiens | - |
hippocampus | hippocampus-stratum lucidum | Homo sapiens | - |
kidney | - |
Homo sapiens | - |
liver | - |
Homo sapiens | - |
medial temporal lobe | - |
Homo sapiens | - |
prefrontal cortex | - |
Homo sapiens | - |
prostate | - |
Homo sapiens | - |
small intestine | - |
Homo sapiens | - |
spinal cord | - |
Homo sapiens | - |
spleen | - |
Homo sapiens | - |
trachea | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-acetyl-L-aspartyl-L-glutamate + H2O | - |
Homo sapiens | N-acetyl-L-aspartate + L-glutamate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GCPII | - |
Homo sapiens |
glutamate carboxypeptidase II | - |
Homo sapiens |
Prostate-specific membrane antigen | - |
Homo sapiens |
PSMA | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0000015 | - |
(S)-2-(3-((S)-1-carboxy-2-(4-hydroxy-3-iodophenyl)ethyl)ureido)pentanedioic acid | - |
Homo sapiens |