Literature summary for 3.4.17.21 extracted from

Serval, V.; Galli, T.; Glowinski, J.; Lavielle, S.
In vitro and in vivo inhibition of N-acetyl-L-aspartyl-L-glutamate catabolism by N-acetylated L-glutamate analogs (1992), J. Pharmacol. Exp. Ther., 260, 1093-1100.

Search for more literature for 3.4.17.21

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	N-acetyl-L-Asp-D-Glu	Rattus norvegicus
N-(3,4-Dicarboxybutanoyl)glutamic acid	-	Rattus norvegicus
N-(Dicarboxymethyl)acetylglutaminic acid	-	Rattus norvegicus
N-Acetyl-beta-L-Asp-L-Glu	-	Rattus norvegicus
N-Succinyl-L-Glu	-	Rattus norvegicus
Quisqualic acid	-	Rattus norvegicus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0005	-	N-Acetyl-L-Asp-L-Glu	no addition of Zn2+ to assay medium	Rattus norvegicus
0.0008	-	N-Acetyl-L-Asp-L-Glu	addition of Zn2+ to assay medium	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Rattus norvegicus	16020	-

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zn2+	metalloproteinase, 1 mM ZnCl2 increases activity 2-3fold	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Rattus norvegicus	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)