Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | 1 mM, complete inhibition | Rattus norvegicus | |
potato carboxypeptidase inhibitor | 10 microM, complete inhibition | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.191 | - |
angiotensin II | pH 8.1, 37°C | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
from mesenteric arterial bed perfusate | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
artery | mesenteric arterial bed, enzyme is identical with its pancreatic counterpart | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin II + H2O | - |
Rattus norvegicus | angiotensin-(1-7) + L-Phe | - |
? | |
angiotensin-(1-12) + H2O | - |
Rattus norvegicus | angiotensin I + ? | conversion of Ang-(1-12) to Ang I proceeds through stepwise cleavage of C-terminal Tyr and Leu residues | ? | |
benzyloxycarbonyl-Val-Phe + H2O | - |
Rattus norvegicus | benzyloxycarbonyl-Val + L-Phe | - |
? |