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Literature summary for 3.4.17.12 extracted from

  • Sun, X.; Wiesner, B.; Lorenz, D.; Papsdorf, G.; Pankow, K.; Wang, P.; Dietrich, N.; Siems, W.E.; Maul, B.
    Interaction of angiotensin-converting enzyme (ACE) with membrane-bound carboxypeptidase M (CPM) - a new function of ACE (2008), Biol. Chem., 389, 1477-1485.
    View publication on PubMed
Search for more literature for 3.4.17.12

Activating Compound

Activating Compound Comment Organism Structure
additional information there is a spatial proximity and interaction between angiotensin-converting enzyme and endogenous carboxypeptidase M in CHO cells, as well as a weak but detectable release of glycosylphosphatidylinositol-anchored carboxypeptidase M evoked by co-localized between angiotensin-converting enzyme Cricetulus griseus
additional information there is a spatial proximity and interaction between angiotensin-converting enzyme and endogenous carboxypeptidase M in MDCK cells, as well as a weak but detectable release of glycosylphosphatidylinositol-anchored carboxypeptidase M evoked by co-localized between angiotensin-converting enzyme Canis lupus familiaris

Inhibitors

Inhibitors Comment Organism Structure
(2-guanidinoethylmercapto)succinic acid
-
 Canis lupus familiaris
(2-guanidinoethylmercapto)succinic acid
-
 Cricetulus griseus
DL-2-mercaptomethyl-3-guanidinoethylthiopropanoic acid specific carboxypeptidase M inhibitor Canis lupus familiaris
DL-2-mercaptomethyl-3-guanidinoethylthiopropanoic acid specific carboxypeptidase M inhibitor Cricetulus griseus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Cricetulus griseus 16020
-
membrane
-
 Canis lupus familiaris 16020
-

Organism

Organism UniProt Comment Textmining
Canis lupus familiaris
-
-
-
Cricetulus griseus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
 Cricetulus griseus
glycoprotein
-
 Canis lupus familiaris

Source Tissue

Source Tissue Comment Organism Textmining
CHO cell
-
 Cricetulus griseus
-
Madin-Darby canine kidney cell
-
 Canis lupus familiaris
-
MDCK cell
-
 Canis lupus familiaris
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dansyl-L-Ala-L-Arg + H2O
-
 Cricetulus griseus dansyl-L-Ala + L-Arg
-
 ?
dansyl-L-Ala-L-Arg + H2O
-
 Canis lupus familiaris dansyl-L-Ala + L-Arg
-
 ?

Synonyms

Synonyms Comment Organism
CPM
-
 Cricetulus griseus
CPM
-
 Canis lupus familiaris