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Literature summary for 3.4.17.1 extracted from

  • Ke, S.; Wright, J.C.; Kwon, G.S.
    Avidin-biotin-PEG-CPA complexes as potential EPR-directed therapeutic protein carriers: preparation and characterization (2007), Bioconjug. Chem., 18, 1644-1650.
    View publication on PubMed

Application

Application Comment Organism
medicine the avidin-biotin-PEGylated-carboxypeptidase complex has a great potential as a therapeutic protein delivery system for solid tumor prodrug targeting Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
105700
-
biotin-PEG(5000)-carboxypeptidase complex, stoichiometry with avidin 1 : 1, determined by MALDI-TOF Bos taurus
142300
-
biotin-PEG(3400)-carboxypeptidase complex, stoichiometry with avidin 1 : 2, determined by MALDI-TOF Bos taurus
146300
-
biotin-PEG(3400)-carboxypeptidase-PEG(2000) complex, stoichiometry with avidin 1 : 2, determined by MALDI-TOF Bos taurus
233000
-
biotin-PEG(5000)-carboxypeptidase-PEG(2000) complex, stoichiometry with avidin 1 : 4, determined by MALDI-TOF Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
the biotin-PEGylated carboxypeptidase complex is purified by gel filtration Bos taurus

Synonyms

Synonyms Comment Organism
carboxypeptidase a
-
Bos taurus
CPA
-
Bos taurus