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Literature summary for 3.4.17.1 extracted from

  • Phoon, L.; Burton, N.A.
    Assessment of a mechanism for reactive inhibition of carboxypeptidase A with QM/MM methods (2005), J. Mol. Graph. Model., 24, 94-101.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
N-(2-chloroethyl)-N-methylphenylalanine both enantiomers, computational analysis of the mechanism for reactive inhibition, quantum mechanical and molecular mechanical methods, the inhibitor enantiomers both bind at the active site and perform nucleophilic deactivation involving cofactor Zn2+, overview Bos taurus

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+
-
Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-