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Literature summary for 3.4.17.1 extracted from

  • Jin, J.Y.; Tian, G.R.; Kim, D.H.
    Optically active 2-benzyl-3-methanesulfinylpropanoic acid: Synthesis and evaluation as inhibitors for carboxypeptidase A (2003), Bioorg. Med. Chem., 11, 4377-4381.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
(2R,4S)-2-benzyl-3-methanesulfinylpropanoic acid
-
Bos taurus
(2S,4R)-2-benzyl-3-methanesulfinylpropanoic acid
-
Bos taurus
(2S,4S)-2-benzyl-3-methanesulfinylpropanoic acid
-
Bos taurus
(R)-2-benzyl-3-(methylthio)propanoic acid
-
Bos taurus
(RS)-2-benzyl-3-(methylthio)propanoic acid
-
Bos taurus
(S)-2-benzyl-3-(methylthio)propanoic acid
-
Bos taurus
additional information no inhibition by (2R,4R)-2-benzyl-3-methanesulfinylpropanoic acid Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
O-(trans-p-chlorocinnamoyl)-L-beta-phenyllactate + H2O
-
Bos taurus ?
-
?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.1
-
(RS)-2-benzyl-3-(methylthio)propanoic acid pH 7.5 Bos taurus
0.56
-
(2S,4S)-2-benzyl-3-methanesulfinylpropanoic acid pH 7.5 Bos taurus
0.74
-
(S)-2-benzyl-3-(methylthio)propanoic acid pH 7.5 Bos taurus
1.46
-
(R)-2-benzyl-3-(methylthio)propanoic acid pH 7.5 Bos taurus
2.79
-
(2R,4S)-2-benzyl-3-methanesulfinylpropanoic acid pH 7.5 Bos taurus
3.86
-
(2S,4R)-2-benzyl-3-methanesulfinylpropanoic acid pH 7.5 Bos taurus