Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | noncompetitive | Homo sapiens | |
1,10-phenanthroline | noncompetitive | Rattus norvegicus | |
DL-2-mercaptomethyl-3-guanidinoethylthiopropanoic acid | competitive | Homo sapiens | |
DL-2-mercaptomethyl-3-guanidinoethylthiopropanoic acid | competitive | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.063 | - |
dansyl-L-Ala-L-Arg | pH 5.6, 37°C | Homo sapiens | |
0.132 | - |
dansyl-L-Ala-L-Arg | pH 5.6, 37°C | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
Golgi apparatus | mainly trans-Golgi network | Homo sapiens | 5794 | - |
nucleus | 98% of enzymic activity | Rattus norvegicus | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
cytokine-inducible isoform CPD-N with incomplete N-terminal domain and intact domains II and III | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
MCF-7 cell | exclusive expression of 180 kDa isoform | Homo sapiens | - |
Nb2 cell | T-lymphoma cell, exclusive synthesis of isoform SPD-N | Rattus norvegicus | - |
Nb2-Sp cell | lymphoma cell, exclusive synthesis of isoform SPD-N | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dansyl-L-Ala-L-Arg + H2O | - |
Homo sapiens | dansyl-L-Ala + L-Arg | - |
? | |
dansyl-L-Ala-L-Arg + H2O | - |
Rattus norvegicus | dansyl-L-Ala + L-Arg | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | enzyme co-immunoprecipitates with protein phosphatase 2A and alpha4 phosphoprotein | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.6 | - |
- |
Rattus norvegicus |
5.6 | - |
and 6.5-7.0. Activity maximum at pH 5.6 is due to activity of domain II, at pH 6.5-7.0 due to domain I | Homo sapiens |
6.5 | 7 | and 5.6. Activity maximum at pH 5.6 is due to activity of domain II, at pH 6.5-7.0 due to domain I | Homo sapiens |