Cloned (Comment) | Organism |
---|---|
expressed in insect cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
A251E | the mutant shows increased activity compared to the wild type cathepsin A | Homo sapiens |
K355Q | the mutant shows increased activity compared to the wild type cathepsin A | Homo sapiens |
L354D | the mutant shows decreased activity compared to the wild type cathepsin A | Homo sapiens |
P451A | the mutant shows increased activity compared to the wild type cathepsin A | Homo sapiens |
R20A | the mutant shows decreased activity compared to the wild type cathepsin A | Homo sapiens |
W382A | the mutant shows decreased activity compared to the wild type cathepsin A | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
32000 | - |
mature enzyme, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P10619 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
fibroblast | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
lysosomal neuraminidase-1 + H2O | lysosomal neuraminidase-1 gains full catalytic activity in the lysosome through its binding to PPCA | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PpcA | - |
Homo sapiens |
protective protein/cathepsin A | - |
Homo sapiens |